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Pulmonary Nodule Radiotherapy Follow-up using Dynamic Contrast Enhancement CT Host Publication: Seventh Belgian Day on Biomedical Engineering Authors: P. Clerinx, R. Deklerck, K. Nieboer, S. Bral, D. Verellen, G. Storme and J. De Mey Publication Date: Nov. 2007
Abstract: Although sound methods exist to derive physical perfusion parameters like regional blood volume, blood flow and permeability from dynamic contrast enhanced studies, we found that these methods require a higher temporal resolution than currently is practically achievable for volumetric CT with full nodule coverage. Yet, the elaborated average enhancement color overlays allow for easy, semi-quantitative evaluation of therapy response by radiologists. The methodology developed in this study provides hence a useful tool that can be used in clinical practice to evaluate tumour response as a viable alternative to the less prevalent PET imaging modality.
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