|
|
EEG Dominant Frequency Peak Differentiates Between Alzheimer's Disease and Frontotemporal Lobar Degeneration This publication appears in: Journal of Alzheimer's Disease Authors: J. Goossens, J. Laton, J. Van Schependom, J. Gielen, H. Struyfs, S. Van Mossevelde, T. Van den Bossche, J. Goeman, P. Paul De Deyn, A. Sieben, J. Martin, C. Van Broeckhoven, J. van der Zee, S. Engelborghs and G. Nagels Volume: 55 Issue: 1 Pages: 53-58 Publication Year: 2017
Abstract: We investigated the power of EEG as biomarker in differential diagnosis of Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD). EEG was recorded from 106 patients with AD or FTLD, of which 37 had a definite diagnosis, and 40 controls. Dominant frequency peaks were extracted for all 19 channels, for each subject. The average frequency of the largest dominant frequency peaks (maxpeak) was significantly lower in AD than FTLD patients and controls. Based on ROC analysis, classification could be made with diagnostic accuracy of 78.4%. Our findings show that quantitative analysis of EEG maxpeak frequency is an easy and useful measure for differential dementia diagnosis.
|
|
